Strengthen your defence with this Fantasy Premier League tips Gameweek 22 defenders round-up and unlock your fantasy football potential.

Recommended defender picks for this Gameweek include players from Manchester City, Liverpool, Sheffield United and Newcastle United.

🌟 João Cancelo MCI, £6

Having sat out the 1-0 win over Sheffield Utd, he’s an absolute certainty to start at Burnley and probably for the next few games at least.

🌟 Trent Alexander-Arnold LIV, £7.3

Has showed signs of returning to top form ahead of the home fixture against Brighton.

🌟 Ethan Ampadu SHU, £4.3

Sheffield Utd have been looking more like their old selves going into the back-to-back home matches against West Brom and Chelsea.

🌟 Jamal Lewis NEW, £4.2

Got an assist in the 2-0 win at Everton, earning him an 11-point haul, and next up for Newcastle are successive home games against Crystal Palace and Southampton.